Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Respiratory failure
ADR ID BADD_A03813
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.04      Respiratory acidoses
14.01.04.003      Respiratory failure
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.06      Respiratory failures (excl neonatal)
22.02.06.002      Respiratory failure
Description A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. [CTCAE] Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code 10038695
MeSH ID D012131; D012131; D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Failure respiratory | Other pulmonary insufficiency, not elsewhere classified | Pulmonary insufficiency following trauma and surgery | Respiration failure | Respiratory failure | Respiratory failure (excl neonatal) | Respiratory insufficiency | Ventilatory failure | Pulmonary failure | Hypercapnic respiratory failure | Restrictive respiratory insufficiency | Respiratory failure aggravated | Hypoxic respiratory failure | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00312Bupropion--
BADD_D00318Busulfan0.000208%
BADD_D00319Butabarbital--
BADD_D00324Butorphanol--
BADD_D00329Cabergoline0.005744%
BADD_D00330Cabozantinib--
BADD_D00344Canagliflozin--
BADD_D00349Capecitabine--
BADD_D00354Captopril0.000583%
BADD_D00356Carbamazepine0.002965%
BADD_D00364Carboplatin0.003683%
BADD_D00367Carfilzomib0.001181%
BADD_D00372Carteolol--
BADD_D00373Carteolol hydrochloride--
BADD_D00374Carvedilol0.000148%
BADD_D00376Caspofungin0.000644%
BADD_D00377Caspofungin acetate--
BADD_D00379Cefadroxil0.000667%
BADD_D00390Cefotaxime0.000213%
BADD_D00398Ceftaroline fosamil0.000056%
BADD_D00399Ceftazidime0.000426%
BADD_D00405Ceftriaxone0.061278%
BADD_D00407Cefuroxime--
BADD_D00410Celecoxib--
BADD_D00412Cephalexin0.000030%
BADD_D00414Ceritinib0.000208%
BADD_D00429Chlorambucil0.000347%
BADD_D00448Chlorthalidone0.000769%
BADD_D00460Ciclesonide0.000410%
BADD_D00474Cisplatin0.001598%
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